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Contact UsThe company focuses on the research, development, production, and sales of chemical raw materials and their formulations. All products have passed national GMP certification, and core products have successively passed official pharmaceutical regulatory certifications from multiple countries, including the EU EDQM, US FDA, Japanese PMDA, and South Korean MFDS. Following its successful listing on the Shenzhen Stock Exchange's ChiNext board on April 4, 2023, Keyuan Pharmaceutical has entered a phase of rapid development driven by both digital intelligence and capital, with its business spanning dozens of countries and regions worldwide.
Sulfonation reaction technology
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Process Qualifications National 18 categories of key regulated hazardous chemical process qualifications Core Technology Full-process automated sulfonation reaction platform Core Advantages 1. Improve production efficiency Shorten reaction time: Through the integrated online infrared detection, automatic feeding module, temperature and pressure monitoring and control modules and other automatic control systems, precisely control the sulfonation reaction time and reaction progress. Reduce per unit acid consumption: By online real-time monitoring of the reaction process, ensuring that the acid consumption is within a reasonable range, improving the utilization rate of raw materials. 2. Reduce environmental pollution Reduce wastewater discharge: By precisely controlling the reaction process, the three wastes are controlled to the lowest level, realizing the green economy of the reaction. Improve waste treatment efficiency: Using an interwall condenser instead of a direct condenser in the direct condenser can significantly reduce the amount of wastewater and increase the concentration of organic matter in the wastewater, which is conducive to recovery and treatment.
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3. Improve product quality and selectivity Optimize heat and mass transfer performance: The structural characteristics of the sulfonation reactor directly affect the quality and selectivity of the sulfonation products. The improved reactor has significantly improved heat and mass transfer performance. Improve product purity: When chlorosulfonic acid is used as the sulfonating agent, the reaction is highly active and the conditions are mild, resulting in a purer product. The byproduct hydrogen chloride can be discharged under negative pressure, which helps the reaction to proceed completely. 4. Enhance operational safety Reduce corrosion risk: Although chlorosulfonic acid is highly corrosive, the improved design, such as adding an alkali absorption tower, can effectively treat the hydrogen chloride gas in the exhaust gas, reducing corrosion on equipment and environmental pollution. Improved automation level: The application of the automatic control system reduces the need for manual operation, improving the safety and stability of operation. 5. Enhance process flexibility Flexible design: According to the characteristics of unit operations, flexible design is carried out, so that the platform can adapt to a variety of fine chemical low-risk and high-efficiency production common technologies, especially for sulfonation reactions, which are highly versatile and can be matched with the process with minor modifications for different substrates and operating conditions. Wide range of applications: In addition to sulfonation reactions, due to the full-process automation design of the platform, it can be applied to other chemical reaction types with more intense heat release, expanding the application range of the platform. Equipment configuration: 300-1000L glass-lined reactor (flexible matching according to scale), combined variable frequency stirring system (speed 10~200rpm stepless regulation), 5000L waste liquid distillation kettle (material: enamel) |
Address: No. 26, Keyuan Street, Shanghe County, Jinan City, Shandong Province
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